Publications

1. Van Elzelingen W, Goedhoop J, Warnaar P, Denys D, Arbab T, Willuhn I. A unidirectional but not uniform striatal landscape of dopamine signaling for motivational stimuli. PNAS (2022).

2. Montalban E, Giralt A, Taing, L et al. Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects. Molecular Psychiatry, 27, 2068-2079 (2022).

3. Van Elzelingen W, Warnaar P, Matos J. Striatal dopamine signals are region specific and temporally stable across action-sequence habit formation, Current Biology, 32, 1163-1174.e6 (2022).

4. Bouland GA, Mahfouz A, Reinders MJT. Differential analysis of binarized single-cell RNA sequencing data captures biological variation, NAR Genomics and Bioinformatics, 3, lqab118 (2021).

5. Bakken TE, Jorstad NL, Hu Q et al. Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature, 598, 111–119 (2021).

6. Wightman DP, Jansen IE, Savage JE et al. A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease. Nature Genetics, 53, 1276–1282 (2021).

7. Berg J, Sorensen SA, Ting JT et al. Human neocortical expansion involves glutamatergic neuron diversification. Nature, 598, 151–158 (2021).

8. Uffelman E, Huang QQ, Munung NS, et al. Genome-wide association studies. Nature Reviews Methods Primers, 1, p. 59 (2021).

9. Keo A, Dzyubachyk O, van der Grond J, et al. Cingulate networks associated with gray matter loss in Parkinson’s disease show high expression of cholinergic genes in the healthy brain. European Journal of Neurosciences, 53, 3727-3739 (2021).

10. Moro A, Van Nifterick A, Toonen RF, Verhage M. Dynamin controls neuropeptide secretion by organizing dense-core vesicle fusion sites. Science Advances, 7 (2021).

11. Aevermann BD, Zhang Y, Novotny M, et al. A machine learning method for the discovery of minimum marker gene combinations for cell-type identification from single-cell RNA sequencing. Genome Research (2021).

12. Michielsen L, Reinders MJT, Mahfouz A. Hierarchical progressive learning of cell identities in single-cell data. Nature Communications, 12, 2799 (2021).

13. De Kloet SF, Bruinsma B, Terra H, et al. Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum. Nature Communications, 12, 1994 (2021).

14. Robinson RA, Griffiths SC, Van de Haar LL, et al. Simultaneous binding of guidance cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2103-2120 (2021).

15. Meijer M, Keo A, van Leeuwen JMC, Dzyubachyk O, Meijer OC, Vinkers CH, Mahfouz A. Molecular characterization of the stress network in individuals at risk for schizophrenia. Neurobiology of Stress, 14, 100307 (2021).

16. Abdelaal T, De Raadt P, Lelieveldt BPF, Reinders M, Mahfouz A. SCHNEL: scalable clustering of high dimensional single-cell data. Bioinformatics, 36, i849-i856 (2020).

17. Terra H, Bruinsma B, de Kloet SF, van der Roest M, Pattij T, Mansvelder HD. Prefrontal cortical projection neurons targeting dorsomedial striatum control behavioral inhibtion. Current Biology, 30, 4188-4200 (2020).

18. Uffelman E, Posthuma D. Emerging methods and resources for biological interrogation of neuropsychiatric polygenic signal. Biological Psychiatry, 89, 41-53 (2020).

19. Charrout M, Reinders MJT, Mahfouz A. Untangling biological factors influencing trajectory inference from single cell data. Bioinformatics, 2 (2020).

20. Verhage M, Sørensen JB. SNAREopathies: Diversity in mechanisms and symptoms. Neuron, 107, 22-37 (2020).