BRAINSCAPES

The aim of BRAINSCAPES is to map in detail the biological mechanisms underlying multiple brain disorders ('brainscaping').

Recent genetic discovery studies have provided unprecedented insight into the genes involved in brain disorders. The next step is to use this knowledge for gaining mechanistic disease insight. In BRAINSCAPES we will develop novel analytic and experimental tools to study the functional consequences of risk genes on the function of specific cells, their circuits and functional output. We aim to provide insight into the molecular and cellular basis of complex brain disorders that can be used to design novel treatments.

News

February 19, 2021 / our-news

Brainscapes PIs join AI in Computational Life-Science program to enhance drug discovery in the brain

The possibilities to access the molecular data of cells and tissues are increasing, but this also creates new challenges.
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February 5, 2021 / our-news

KHMW Young Talent Award for Lieke Michielsen

The Royal Holland Society of Sciences and Humanities (KHMW) has awarded Lieke Michielsen (Delft University of Technology) a Pfizer Prize for Life Sciences 2020.
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January 22, 2021 / our-news

Exploring prefrontal brain mechanisms underlying behavioral inhibition

Terra et al. investigate the role of specific cortical neuron types that send projections from dorsal mPFC-to-medial dorsal striatum in behavioral inhibition.
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December 18, 2020 / our-news

Martijn van den Heuvel awarded ERC Consolidator grant

Computational neuroscientist Martijn van den Heuvel has been awarded a Consolidator Grant by the European Research Council (ERC).
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June 19, 2020 / our-news

SNAREopathies: new syndrome classification based on mechanism

A position paper by Brainscapes partner Matthijs Verhage (VU University), and Jakob Sørensen (University of Copenhagen), published in Neuron on June 19, proposes to unify syndromes caused by mutations in eight core components of the synaptic secretion machinery, based on common etiology and mechanism.
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