BRAINSCAPES

The aim of BRAINSCAPES is to map in detail the biological mechanisms underlying multiple brain disorders ('brainscaping').

Recent genetic discovery studies have provided unprecedented insight into the genes involved in brain disorders. The next step is to use this knowledge for gaining mechanistic disease insight. In BRAINSCAPES we will develop novel analytic and experimental tools to study the functional consequences of risk genes on the function of specific cells, their circuits and functional output. We aim to provide insight into the molecular and cellular basis of complex brain disorders that can be used to design novel treatments.

News

July 27, 2021

Frank Meye receives Vidi grant

Assistant professor Frank Meye is a valuable Brainscapes member who studies the influence of  stress on the strength of connections in the brain.
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May 18, 2021 / our-news

A new model to continuously learn cell identities in single-cell data

In a recent Nature Communications paper from Brainscapes, Michielsen et al. developed a machine learning method to build cellular hierarchies by combining the annotations of multiple datasets.
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April 9, 2021 / our-news

Uncovering functionally distinct anatomical circuits within the PFC

De Kloet et al. show that mPFC output pathways targeting anatomically and functionally distinct striatal and thalamic subregions encode bi-directional command of cognitive control.
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April 1, 2021 / our-news

Seed grant for OCD-related DBS research

He will receive $800,000 over four years for exploring neural mechanisms of deep-brain stimulation in a mouse model for OCD.
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