Learning increases structural and functional plasticity of engram cell synapses. This enhanced synaptic connectivity is thought to underlie memory recall to natural cues. We aim to examine the structural and molecular landscape of these memory storing synapses using a combination of synapse labelling, imaging, isolation and mass spectrometry.
Access: More information related to these datasets can be obtained by request and will be made available via the journal and/or in public repositories upon publication, as described above. Specifically the proteomics data (i.e. raw mass spec output files, peptide/protein identification files) will be listed in the PRIDE database. Source data for experiments (as an excel file) will be made part of the published article (and may include other kinds of data, e.g. synapse structural data). Sample numbers and other details depend on the experiment and will be explicitly mentioned in the article and/or as a metadata file for repository uploads.